
The finding was largely encouraging but contained a clear warning sign: Even though the vaccine generated disease-fighting antibodies that worked against the South African variant, that efficacy was diminished. Moderna said there was a reduction in response, prompting the company to design a new potential vaccine that could be added to the current two-dose regimen.
As a precaution, Moderna announced that it will begin two new studies. The company will test adding a third shot of its current vaccine to boost its two-dose regimen. The biotechnology company also plans early human tests of the all-new vaccine specific to the South African variant, using it as a booster to prime the immune system to the new strain.