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The pilot of the F-35B Lightning II jet ejected safely from the aircraft, according to a statement from Joint Base Charleston.
"If you have any information that may help our recovery teams locate the F-35, please call the Base Defense Operations Center at 843-963-3600," the base said on X, formerly known as Twitter.
The fighter jet's main advantages, according to its manufacturer, Lockheed Martin (LMT.N), are that it is nearly impossible to track with radar and is packed with advanced sensors and other gear.