Deliberately damaging the thyroid will produce a plethora of symptoms affecting the entire human body from head to toe. Symptoms of thyroid damage and fluoride poisoning include weight gain, edema, kidney disease, kidney failure, hair loss, depression, aggression, aches, pains, skin problems, bone deformities (likely including "arthritis" and spontaneous fractures), sexual/erectile dysfunction, memory loss, weakness, fatigue, heart disease, irritability, cancer, digestive disorders including severe GERD as a result of swallowing fluoride, nausea, vomiting, visual problems, gum disease, "high cholesterol," connective tissue damage, brittle teeth, wrinkles, premature aging, dehydration, and long, long after the whole body has been damaged, "cosmetic fluorosis" might finally show up in a tooth or two. "Cosmetic fluorosis" is usually the only sign of fluoride poisoning mentioned by fluoride promoters, while downplaying the rest of the signs as though their livelihoods depended upon it.