This particular e.coli variation is a member of the O104 strain, and O104 strains are almost never (normally) resistant to antibiotics. In order for them to acquire this resistance, they must be repeatedly exposed to antibiotics in order to provide the "mutation pressure" that nudges them toward complete drug immunity.
So if you're curious about the origins of such a strain, you can essentially reverse engineer the genetic code of the e.coli and determine fairly accurately which antibiotics it was exposed to during its development. This step has now been done (see below), and when you look at the genetic decoding of this O104 strain now threatening food consumers across the EU, a fascinating picture emerges of how it must have come into existence.
So how, exactly, does a bacterial strain come into existence that's resistant to over a dozen antibiotics in eight different drug classes and features two deadly gene mutations plus ESBL enzyme capabilities?




MILLIONS of women facing an elevated risk for breast cancer could slash their chances of getting the widely feared malignancy by taking a hormone-blocking pill used to treat the disease or prevent a recurrence, researchers say.
As a part of the deal struck that year, Haiti would join the Venezuelan-led oil alliance known as PetroCaribe and it would purchase oil “only 60 percent up front with the remainder payable over twenty-five years at 1 percent interest” — a remarkably good deal for the Western hemisphere’s poorest country.
Julian Assange, the WikiLeaks founder, has won the 2011 Martha Gellhorn prize for journalism.
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The bacterium that has killed more than a dozen Europeans, sickened nearly 2,000 more and raised international alarms would be legal if it were found on meat or poultry in the United States.





























