Since September, 16 major drug companies have inked deals with the Trump administration to lower prices. But in January — the time of year when pharmaceutical companies typically roll out price hikes — all 16 companies released higher list prices for some of their drugs.
The agreements, nicknamed "most favored nation" deals, were aimed at getting lower prices for American consumers and pushing other wealthy countries to pay higher prices for new drugs.
But drug companies, including the 16 that made deals, raised the prices of 872 brand-name drugs in the first two weeks of 2026, according to a new analysis by 46brooklyn, a drug price research firm.The drugs with price hikes included medicines to treat cancer, heart failure and Type 2 diabetes. The price of some COVID shots also went up.
"The real truth serum is what's happening in the marketplace after those deals occur," says Antonio Ciaccia, CEO of 46brooklyn, a nonprofit that tracks the list prices of prescription medications. "January is prime time for list price changes on brand-name drugs. So in examining where we are today, we're pretty much in line with the last few years."




Donald Trump’s so-called “board of peace” has been announced as the US president seeks to manage the reconstruction of Gaza and its transitional administration amid a fragile ceasefire agreement between Israel and Hamas.
A US federal judge in Boston on Friday gave the Trump administration three weeks to “rectify the mistake” it made by deporting a college student to Honduras while she was traveling home to visit her family for Thanksgiving as he recommended it issue her a student visa.
One-year-old Mohammed Bassiouni died of exposure to the cold on Tuesday. It was his first birthday.
Israeli Prime Minister Benjamin Netanyahu has cast the U.S. announcement that the fragile ceasefire in Gaza would advance to its second phase as largely symbolic, raising questions about how its more challenging elements will be carried out.
Ukrainian troops from the National Guard’s 13th “Khartia” Brigade repelled a large-scale Russian assault in the Kharkiv region, killing about 70 Russian soldiers.





























